By Paul Keall, Tokihiro Yamamoto, Yelin Suh (auth.), Jan Ehrhardt, Cristian Lorenz (eds.)
Respiratory movement motives an incredible uncertainty in radiotherapy making plans of the thorax and higher stomach. the most target of radiation remedy is to get rid of or diminish tumor cells with out destructive the encircling tissue through providing a excessive radiation dose to the tumor quarter and a dose as little as attainable to fit organ tissues. assembly this call for is still a problem particularly in case of lung tumors because of breathing-induced tumor and organ movement the place movement amplitudes can degree as much as numerous centimeters. accordingly, modeling of respiration movement has develop into more and more vital in radiation remedy. With 4D imaging innovations spatiotemporal snapshot sequences will be bought to enquire dynamic methods within the patient’s physique. in addition, snapshot registration allows the estimation of the breathing-induced movement and the outline of the temporal swap in place and form of the constructions of curiosity by way of setting up the correspondence among pictures got at various levels of the respiring cycle. In radiation remedy those movement estimations are used to outline exact remedy margins, e.g. to calculate dose distributions and to strengthen prediction types for gated or robot radiotherapy. during this e-book, the expanding position of photograph registration and movement estimation algorithms for the translation of complicated 4D scientific picture sequences is illustrated. diversified 4D CT picture acquisition ideas and conceptually diversified movement estimation algorithms are provided. The medical relevance is confirmed by way of instance purposes that are concerning the radiation treatment of thoracic and belly tumors. The cutting-edge and views are proven by way of an perception into the present box of analysis. The e-book is addressed to biomedical engineers, clinical physicists, researchers and physicians operating within the fields of scientific photo research, radiology and radiation therapy.
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Extra resources for 4D Modeling and Estimation of Respiratory Motion for Radiation Therapy
Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 53(4), 822–834 (2002) 68. : Detection of lung tumor movement in real-time tumor-tracking radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 51(2), 304–310 (2001) 69. : Non-invasive imaging of regional lung function using X-ray computed tomography. J. Clin. Monit. Comput. 16(5–6), 433–442 (2000) 70. : Regional ventilation and lung mechanics using X-ray CT.
Med. Phys. 32(9), 2850–2861 (2005) 24. : Conformal radiotherapy (CRT) planning for lung cancer: analysis of intrathoracic organ motion during extreme phases of breathing. Int. J. Radiat. Oncol. Biol. Phys. 51(4), 1081–1092 (2001) 25. : Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation. Int. J. Radiat. Oncol. Biol. Phys. 57(3), 875–890 (2003) 26.
Conformal radiotherapy (CRT) planning for lung cancer: analysis of intrathoracic organ motion during extreme phases of breathing. Int. J. Radiat. Oncol. Biol. Phys. 51(4), 1081–1092 (2001) 25. : Potential for reduced toxicity and dose escalation in the treatment of inoperable non-small-cell lung cancer: a comparison of intensity-modulated radiation therapy (IMRT), 3D conformal radiation, and elective nodal irradiation. Int. J. Radiat. Oncol. Biol. Phys. 57(3), 875–890 (2003) 26. : Influence of retrospective sorting on image quality in respiratory correlated computed tomography.